Medical Purified Water Treatment System | WFI Water Machine | YohoAI
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Home > Products > Purified Water Treatment

Medical Purified Water Treatment System

Double-stage reverse osmosis system for pharmaceutical-grade purified water ??00L/h capacity

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Product Overview

Double-stage RO system for pharmaceutical-grade purified water production

The 500L/h Medical Purified Water Treatment System is designed for pharmaceutical, biotechnology, and healthcare facilities requiring USP-grade purified water. The system uses a double-stage reverse osmosis process to achieve water quality exceeding pharmacopeia standards for purified water.

The complete treatment process includes multi-media filtration, activated carbon adsorption, water softening, cartridge filtration, and dual-pass reverse osmosis. The final product water passes through UV sterilization and 0.22锟斤拷m sterilizing filtration before reaching the point of use.

All pre-treatment stages utilize Fleck automatic control heads imported from the United States, enabling automatic backwashing, forward flushing, and regeneration. The system features self-diagnostic capabilities and automatic protection against low pressure, overpressure, dry run, and other fault conditions.

Medical Purified Water System Process Flow - RO+EDI+UV

Process Flow

Complete treatment train from raw water to purified water point-of-use

Tap Water
Raw Water Tank
Multi-Media Filter
Activated Carbon Filter
Water Softener
Precision Filter (5锟斤拷m)
1st-Stage HP Pump
1st-Stage RO
2nd-Stage HP Pump
2nd-Stage RO
Pure Water Tank
Ozone Sterilizer
Precision Filter (0.22锟斤拷m)
UV Sterilizer
Use Point

How It Works

Multi-stage treatment process with detailed equipment functions

1

Raw Water Intake & Tank

The automatic inlet valve opens based on the liquid level signal from the raw water tank. Low/Medium/High level controls manage solenoid valves for safe operation. A manual bypass valve provides emergency backup if the automatic valve fails.

2

Multi-Media Filtration

A quartz sand filter removes particles larger than 20锟斤拷m including silt, rust, colloids, and suspended solids. This protects downstream equipment and extends the service life of subsequent treatment stages.

3

Activated Carbon Adsorption

The activated carbon filter removes pigments, odors, organic matter, residual chlorine, and pesticide contamination. This critical step protects RO membranes from chlorine damage and improves product water taste and odor.

4

Water Softening

The softening filter reduces water hardness by removing calcium and magnesium ions (scale) through ion exchange. Intelligent resin regeneration ensures continuous softening capability with minimal maintenance.

5

Precision Filtration (5锟斤拷m)

A 5锟斤拷m cartridge filter captures damaged filter media and particles that passed through pre-treatment. This protects RO membranes from clogging and ensures required inlet water quality for the RO system.

6

First-Stage Reverse Osmosis

Contamination-resistant Hyde Energy spiral-wound RO membranes treat raw water at 0.8-1.2 MPa operating pressure. Each membrane includes a sampling valve for monitoring individual membrane conductivity and performance.

7

pH Adjustment & Second-Stage RO

First-stage RO product water enters a purified water tank where food-grade sodium hydroxide adjusts pH. The second-stage RO system further purifies water, with concentrate returned to the raw water tank for recycling.

8

Ozone Sterilization

Ozone sterilization provides bacteriolytic-grade disinfection that leaves no residue. It has broad-spectrum activity against bacteria, spores, viruses, fungi, and can destroy botulinum toxin for complete sterilization.

9

Final Filtration & UV Treatment

A 0.22锟斤拷m sterilizing filter removes dead bacteria and foreign matter. The UV sterilizer provides additional disinfection (note: UV must be turned off when using ozone, as UV converts ozone to oxygen).

10

Delivery to Use Points

Purified water is delivered through a sanitary distribution loop to multiple use points. The system maintains water quality through continuous circulation and periodic sanitization cycles.

Technical Specifications

500L/h medical purified water treatment system

Parameter Specification Notes
System Capacity 500 L/h At 25锟斤拷C water temperature
Product Water Quality Pharmacopeia Purified Water USP/EP/ChP compliant
Raw Water Source Municipal tap water TDS < 500 ppm recommended
Recovery Rate (1st Stage) 50??% Depends on feed water quality
Recovery Rate (2nd Stage) 85??% Higher quality feed water
Pre-Treatment Stages Multi-media + Carbon + Softener Fleck automatic control heads
Cartridge Filter (Pre-RO) 5 锟斤拷m precision filter Protects RO membranes
RO Membrane Type Hyde Energy spiral-wound Contamination-resistant design
1st Stage RO Pressure 0.8??.2 MPa 1.2 MPa = membrane cleaning needed
2nd Stage RO Pressure 0.8??.2 MPa Same as 1st stage
pH Adjustment Food-grade NaOH Maintains constant level
Sterilizing Filter 0.22 锟斤拷m cartridge Removes bacteria & particles
Ozone Generator Integrated unit Bacteriolytic-grade sterilization
UV Sterilizer 254 nm wavelength Additional disinfection layer
Low-Pressure Protection LPS switch Prevents pump dry run
Overpressure Protection HSL switch System shutdown on overpressure
Control System PLC + HMI touch screen Automatic operation & alarms
Material (Wetted Parts) 316L stainless steel / PVC cGMP compliant
Flow Rate Temperature Effect -2.1% per 1锟斤拷C drop Based on 25锟斤拷C baseline

* Specifications subject to final confirmation based on site conditions and water quality analysis. Custom capacities from 250 L/h to 5,000 L/h available.

See It in Action

Watch our purified water treatment system in operation

Live demo ??See the full production process

Key Features

Engineered for medical-grade water purity and reliability

Double-Stage RO

Two-pass reverse osmosis ensures product water meets pharmacopeia standards for purified water. Second-stage concentrate recycled to raw water tank for zero waste.

Multi-Barrier Sterilization

Ozone sterilization + 0.22锟斤拷m filtration + UV treatment provides three layers of protection against bacteria, viruses, and endotoxins.

Automatic Control

Fleck automatic control heads enable self-backwashing, regeneration, and system diagnostics. Minimal manual intervention required.

Safety Protection

Low-pressure switch prevents pump dry run. Overpressure switch provides emergency shutdown. Check valves prevent pressure rebound damage.

Monitoring & Sampling

Individual RO membrane sampling valves allow real-time conductivity monitoring. HMI displays system status, flow rates, and alarm history.

Water Recovery

Second-stage RO concentrate is returned to the raw water tank for recycling. System achieves overall water recovery of 75% or higher.

pH Adjustment

Integrated pH adjustment with food-grade sodium hydroxide maintains optimal water chemistry for pharmaceutical applications.

Easy Maintenance

Modular cartridge filters, quick-connect fittings, and self-maintenance system minimize downtime and operating costs.

Applications

Trusted across pharmaceutical and healthcare industries worldwide

Pharmaceutical Manufacturing

Production of oral solid dosage forms, topical preparations, and other drug products requiring pharmacopeia-grade purified water.

Injectable Production

Pre-treatment for water for injection (WFI) systems, dialysis centers, and sterile manufacturing facilities.

Hospital Pharmacy

Central pharmacy water systems for compounding, IV admixture preparation, and sterile product manufacturing.

Laboratory & Research

Quality control laboratories, R&D centers, and analytical testing facilities requiring high-purity water.

Biotechnology

Cell culture media preparation, buffer solution production, and bioprocessing applications.

Nutraceuticals

Dietary supplement manufacturing, health product production, and functional food processing.

Why Choose YohoAI?

Your trusted partner in pharmaceutical water treatment

Free Installation & Debugging

We provide free on-site installation, debugging, and commissioning for all equipment. Sufficient spare parts, tools, and accessories are included in every shipment.

One-Year Warranty

All products include a 12-month warranty. During the warranty period, technical services, equipment repairs, and parts replacement are covered under our three guarantees policy.

Lifelong Service

Our commitment doesn't end at delivery. We offer lifelong technical support, spare parts supply, and software updates for all customers.

Free Technical Training

We provide free process trials, operator training, and maintenance training at our factory. Our experienced engineers also support process layout design for your facility.

YohoAI Purified Water Treatment System - GMP FDA Compliant

Frequently Asked Questions

Q: What water quality does the system produce?

A: The system produces pharmacopeia-grade purified water meeting USP, EP, and ChP (Chinese Pharmacopeia) standards. The double-stage RO process ensures consistent quality with conductivity typically below 10 锟斤拷S/cm.

Q: How often do RO membranes need cleaning?

A: When operating pressure reaches 1.2 MPa (vs. 0.8 MPa for new membranes), chemical cleaning is required. Under normal operating conditions, this typically occurs every 6-12 months depending on feed water quality.

Q: How does temperature affect production capacity?

A: For every 1锟斤拷C drop in water temperature below 25锟斤拷C, production flow decreases by approximately 2.1%. The system is rated at 500 L/h at 25锟斤拷C baseline temperature.

Q: Can I use UV and ozone sterilization together?

A: No. UV light converts ozone to oxygen, reducing ozone's sterilization effectiveness. Use either UV or ozone treatment at any given time, not both simultaneously.

Q: What is the water recovery rate?

A: The first-stage RO recovery is 50-75%, and the second-stage recovery is 85-90%. Second-stage concentrate is recycled to the raw water tank, achieving overall system recovery of 75% or higher.

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Ready to Start Your Purified Water Project?

Contact our sales team for a free consultation, customized quote, process trial, and factory tour arrangement.

  • No.999 Husong Rd., Songjiang District, Shanghai, China
  • +8613761035942 (WhatsApp)
  • james@yohomachinery.cn
  • Response within 24 hours

Frequently Asked Questions About Purified Water Systems

Common questions from pharmaceutical manufacturers

What standards does your purified water system meet?

Our pharmaceutical purified water treatment systems meet USP (United States Pharmacopeia), EP (European Pharmacopeia), and ChP (Chinese Pharmacopeia) standards. The systems are designed to produce both Purified Water (PW) and Water for Injection (WFI), complying with GMP and FDA requirements.

What is the production capacity of your water treatment systems?

YohoAI offers purified water treatment systems ranging from 100L/h to 5,000L/h capacity. Our standard 500L/h system features dual-stage RO with EDI polishing, achieving water resistivity of 18.2 MOmega-cm. Custom capacities are available for large pharmaceutical manufacturing facilities.

How does the RO+EDI purification process work?

Our water purification process uses multi-stage treatment: pre-filtration, dual-stage reverse osmosis (RO), electro-deionization (EDI), and UV/ozone sterilization. The RO membranes remove 99%+ of dissolved solids, while EDI polishing achieves pharmaceutical-grade purity. The system operates fully automatically with PLC control and real-time monitoring.