Flexible, multi-product rotary tablet press solutions purpose-built for contract development and manufacturing organizations (CDMOs) requiring rapid changeover and full regulatory compliance.
Contract development and manufacturing organizations (CDMOs) face intense pressure to maximize equipment utilization across diverse product portfolios. YohoAI ZP Series rotary tablet presses are engineered for CDMO operations - delivering sub-30-minute product changeover, full regulatory validation packages, and scalable throughput from 50,000 to 400,000 tablets/hour. With 200+ recipe storage on the HMI, FAT/IQ/OQ/PQ documentation included as standard, and 316L stainless steel construction throughout, YohoAI tablet presses minimize downtime and maximize your production flexibility.
Verified factory data - not marketing estimates
Tool-free punch and die removal with pre-set compression recipes stored on the 10-inch HMI. CDMOs can switch between different tablet products rapidly, maximizing equipment uptime and production flexibility.
Pre-store compression parameters for 200+ products on the touch screen HMI. Each recipe includes fill depth, compression force, turret speed, and pre-compression settings for instant recall and zero-error changeovers.
IQ/OQ/PQ documentation, FAT protocols, and EN 10204 3.1/3.2 material certificates ship with every machine. No additional cost for validation support documentation - ready for regulatory submission from day one.
From single ZP-19 units for niche products to multi-press lines with ZP-35 and ZP-55 machines. YohoAI engineers provide complete tablet press line layout and integration support for CDMO facilities.
Audit trail, electronic signatures, and user access controls meet FDA 21 CFR Part 11 requirements for CDMO environments handling multiple clients' proprietary formulations with full data integrity protection.
Complete batch logging with USB and Ethernet data export for client reporting. Audit-compliant records include compression force curves, weight variation data, and turret speed logs per production run.
Our team responds within 2 hours with CIF/CFR/FOB pricing and delivery timeline.
YohoAI ZP Series presses are designed for multi-product CDMO environments with sub-30-minute changeover, 200+ HMI-stored recipes, and tool-free punch removal. Full IQ/OQ/PQ documentation ships as standard, enabling rapid client project onboarding. Throughput ranges from 50,000 to 400,000 tablets/hr, covering R&D through commercial scale.
YohoAI tablet presses for CDMO use range from USD 15,000 (ZP-5 for R&D/pilot) to USD 95,000 (ZP-55 for high-volume commercial lines). Full validation documentation (IQ/OQ/PQ, FAT, material certificates) is included in the standard package with no additional licensing fees. Lead time is 30-60 days for standard configurations.
Yes. YohoAI supplies individual presses and complete turnkey tablet press lines including granulators, feeders, metal detectors, weight checkers, and dust collection systems. Our engineering team provides layout design, installation, commissioning, and IQ/OQ/PQ execution support for new CDMO facility validations.
Absolutely. ZP Series presses are CE certified, cGMP compliant, FDA 21 CFR Part 11 ready, and ISO 9001:2015 certified. They are designed for US FDA, EU EMA, and WHO-prequalified manufacturing. EN 10204 3.1/3.2 material certificates for all 316L SS product contact parts are included for client regulatory submissions.
Yes. YohoAI's Shanghai demo facility can process your actual product or a representative formulation. We can send you filled samples for quality assessment. Demo sessions are typically arranged within 5 working days of inquiry. Video recording of the demo run is provided for internal evaluation.
Pricing varies by configuration and accessories. Please send us your specific requirements including production capacity needs, tube/can/capsule format, and required certifications. We typically respond within 2 hours with CIF/CFR/FOB pricing.
Standard delivery ranges from 30-90 working days depending on the model and configuration. Pharmaceutical GMP configurations with validation documentation packages require additional 5-10 working days. Expedited manufacturing is available for urgent orders at a 15-25% premium.
All YohoAI machines carry CE certification and are designed to meet cGMP and ISO9001 standards. Additional certifications including FDA compliance and specific food-grade standards are available depending on the product line and configuration.
CDMO operations demand maximum equipment utilization across diverse client portfolios, making rapid installation and commissioning critical for project timelines. ZP Series presses ship with FAT protocols and complete IQ/OQ/PQ documentation, enabling fast regulatory qualification for multi-client facilities. The 200+ recipe storage system on the 10-inch HMI allows new clients to be onboarded by simply uploading their compression parameters. YohoAI provides line layout design support for CDMO facilities to optimize floor space utilization when installing multiple ZP presses. Commissioning for a new CDMO line typically takes 3-5 working days including validation documentation execution.
The defining maintenance requirement for CDMO tablet presses is cleaning validation between client projects. Cross-contamination control is paramount when processing proprietary formulations from different clients. Every changeover must follow a documented cleaning SOP verified by analytical testing, especially for potent compounds, hormones, or allergens. The HMI audit trail provides electronic batch records for each client project, including compression force curves, weight variation logs, and changeover records. FDA 21 CFR Part 11 compliance requires user access controls to be configured for each operator with unique login credentials. Client-specific recipes should be password-protected to prevent unauthorized access to proprietary compression parameters.
CDMO maintenance planning must account for multi-shift operations and high changeover frequency. Preventive maintenance schedules should be based on machine hours rather than calendar periods. A spare punch tip inventory for each client's specific tooling configuration should be maintained to avoid production delays. The weighbridge option is particularly valuable for CDMOs handling potent compounds where dosage accuracy directly impacts client quality reports. Annual IQ/OQ/PQ revalidation ensures the equipment remains within validated parameters across all client products. YohoAI offers CDMO-specific service contracts that include priority technical support, on-site stock of critical spare parts, and annual regulatory audit preparation.
Best-selling CDMO workhorse model with 200+ recipe storage and sub-30-minute changeover
Full cGMP validation and FDA 21 CFR Part 11 compliance for contract manufacturing
Entry-level model ideal for early-phase clinical trial and R&D batch manufacturing
