Ultra-high-speed 45-station rotary tablet press delivering up to 360,000 tablets per hour with 150 kN compression force for large-scale pharmaceutical GMP production.
The YohoAI ZP-45 is an ultra-high-speed rotary tablet press engineered for large-scale pharmaceutical and nutraceutical production, delivering up to 360,000 tablets per hour across 45 stations. With 150 kN maximum compression force and Type BB/D punch compatibility, the ZP-45 handles the most demanding tablet formulations including high-density APIs and multi-layer tablets. Every unit is cGMP validated and ships with full IQ/OQ/PQ documentation.
Verified factory data - not marketing estimates
45-station high-speed turret operating at up to 50 rpm delivers industry-leading throughput for large-scale tablet production with consistent quality at every punch station.
Handles high-density APIs, hard-to-compress formulations, and multi-layer tablets with ease. Closed-loop servo force control maintains +/-1% accuracy across all 45 stations.
Dual-layer servo feeder achieves +/-1-2% weight variation per USP <905>. Optional on-line weighbridge reduces variation to +/-0.5% for potent compounds and narrow therapeutic index drugs.
Tool-free punch removal with pre-set recipes stored on HMI. Turret and punch changeover completed in under 30 minutes, minimizing downtime between production runs.
316L SS product contact surfaces, Ra <= 0.4 um polished die table, CIP/WIP compatible. Full audit trail, electronic signatures, and data integrity features meet FDA regulatory requirements.
10-inch touch screen HMI with recipe management for 200+ products, batch logging, audit trail, and Ethernet connectivity for factory-wide SCADA integration and Industry 4.0 readiness.
Our team responds within 2 hours with CIF/CFR/FOB pricing and delivery timeline.
The ZP-45 typically ranges from USD 55,000 to USD 80,000 depending on configuration including optional weighbridge, hardness tester, soundproof enclosure, and IoT remote diagnostics module. Standard lead time is 45-60 days from confirmed purchase order.
The ZP-45 produces up to 360,000 tablets per hour at maximum turret speed of 50 rpm with 45 stations operating. At typical production settings of 35-40 rpm, output is approximately 280,000-310,000 tablets/hour with optimized tablet quality.
The ZP-45 is CE certified, cGMP compliant, and FDA 21 CFR Part 11 ready. Every machine ships with IQ/OQ/PQ validation documentation, FAT protocols, EN 10204 3.1/3.2 material certificates for all 316L SS product contact parts, and a complete O&M manual. Validation support is available from YohoAI's engineering team.
The ZP-45 produces tablet diameters from 6 mm to 22 mm using Type BB/D punches, with a deep-fill option supporting fill depths up to 22 mm. It handles high-density APIs, potent compounds, and double-layer tablet formulations requiring up to 150 kN compression force.
Yes. YohoAI's Shanghai demo facility can process your actual product or a representative formulation. We can send you filled samples for quality assessment. Demo sessions are typically arranged within 5 working days of inquiry. Video recording of the demo run is provided for internal evaluation.
Pricing varies by configuration and accessories. Please send us your specific requirements including production capacity needs, tube/can/capsule format, and required certifications. We typically respond within 2 hours with CIF/CFR/FOB pricing.
Standard delivery ranges from 30-90 working days depending on the model and configuration. Pharmaceutical GMP configurations with validation documentation packages require additional 5-10 working days. Expedited manufacturing is available for urgent orders at a 15-25% premium.
All YohoAI machines carry CE certification and are designed to meet cGMP and ISO9001 standards. Additional certifications including FDA compliance and specific food-grade standards are available depending on the product line and configuration.
The ZP-45 requires a reinforced foundation (minimum 2,500 kg/m2) due to its 2,100 kg mass and high-speed 50 rpm turret operation. Foundation bolts must be grouted before machine leveling with precision spirit level. Electrical connection is 380V/50Hz 3-phase with dedicated motor starter and overload protection. Air supply at 0.6 MPa with oil-water separator is essential for pneumatic controls. The HMI commissioning wizard guides operators through 45-station force mapping and feeder calibration. YohoAI recommends a 3-day on-site commissioning and validation support visit for the ZP-45 to ensure full compliance with GMP documentation requirements.
The ZP-45 operates at higher speeds and forces than smaller models, making strict maintenance discipline critical. Pre-shift punch inspection across all 45 stations is mandatory, with particular attention to punch tip alignment as misalignment at 50 rpm can cause accelerated die wear. The dual-layer servo feeder should be checked for proper lubrication and belt tension before each run. The weighbridge option (for +/-0.5% weight control) requires weekly calibration using certified reference weights. Clean all product-contact surfaces with food-grade sanitizer after every batch, and use dedicated tooling protocols for potent compound formulations to prevent cross-contamination in multi-product facilities.
Quarterly maintenance for the ZP-45 should include vibration analysis of all rotating components, compression roll bearing inspection, and die table lapping quality assessment. The 11 kW main motor should have its insulation resistance tested annually. The HMI operating system and recipe database should be backed up monthly to a USB drive stored in a controlled environment. Due to the machine's high throughput, punch tip replacement intervals should be monitored closely based on actual production counts rather than calendar time. YohoAI's remote diagnostics via Ethernet connection allow real-time monitoring of compression force data and machine health, reducing unplanned downtime in large-scale production facilities.
