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Softgel Encapsulation Solutions for Dietary Supplement Factories

Solve shelf stability, batch consistency, and ROI challenges with RG series rotary die softgel encapsulation equipment.

CE Certified cGMP ISO9001

Dietary supplement factories face three recurring challenges: protecting oxygen-sensitive actives, holding tight batch-to-batch consistency, and justifying equipment ROI. The RG series rotary die encapsulation line addresses each with precision dosing, vegetarian shell options, and scalable capacity from lab to mega-line.

Technical Specifications

Verified factory data - not marketing estimates

Capacity Range
5,000-228,000 caps/hr
Filling Accuracy
+/-1-2%
Shell Materials
Gelatin, HPMC, pullulan
Contact Material
316L stainless steel
Capsule Size
5-24 mm
Sealing
Hydraulic 0.3-0.8 MPa
Drying
25C, 30% RH, 4-8 h
Certifications
CE, cGMP, ISO 9001

Key Features

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Shelf Stability

Nitrogen flushing and leak-proof sealing protect oxygen-sensitive omega-3, CoQ10, and probiotics.

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Batch Consistency

+/-1-2% servo dosing with in-process weight control and auto-reject of off-spec capsules.

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Fast ROI

40-60% savings vs European brands with scalable RG-100 to RG-8800 capacity.

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Vegetarian Options

Standard HPMC and pullulan shells for halal and kosher clean-label supplements.

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Flexibility

15-30 minute die change for multiple shapes and sizes across client formulations.

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Traceability

HMI recipe management and data logging support batch records and audits.

Applications

Vitamin softgel manufacturing Omega-3 fish oil capsules CoQ10 and curcumin supplements Probiotic encapsulation Private label contract manufacturing Sports nutrition brands

Get a Free Quote for Softgel Encapsulation Solutions for Dietary Supplement Factories

Our team responds within 2 hours with CIF/CFR/FOB pricing and delivery timeline.

Frequently Asked Questions

Why choose a softgel encapsulation line for supplements?

Softgels mask taste and odor, improve bioavailability, and protect oxygen-sensitive actives like omega-3 and CoQ10. RG series rotary die machines offer +/-1-2% dosing accuracy, vegetarian HPMC shells, and scalable capacity, making them ideal for supplement factories and contract manufacturers.

How does softgel encapsulation improve shelf stability?

RG series machines use nitrogen flushing and hydraulic sealing at 0.3 to 0.8 MPa for leak-proof capsules. Controlled drying at 25C and 30% relative humidity brings moisture to 6-10 percent, protecting sensitive oils, probiotics, and vitamins from oxidation and extending shelf life.

How does the RG series ensure batch-to-batch consistency?

Servo-controlled dosing pumps deliver +/-1-2% accuracy, with an optional +/-1% precision pump for high-value actives. In-process weight control and automatic rejection of off-spec capsules, plus HMI recipe management, keep every supplement batch within tight specification limits.

What is the ROI of a supplement softgel line?

Chinese RG series machines offer 40 to 60 percent savings versus European brands while meeting CE, cGMP, and ISO 9001 standards. Scalable capacity from 5,000 to 228,000 caps/hr lets factories match investment to demand and expand without replacing equipment.

Which vitamins and actives suit softgel manufacturing?

Common supplement softgels include omega-3 fish oil, vitamin D3 and E, CoQ10, evening primrose oil, flaxseed oil, turmeric curcumin, and collagen. The RG series handles oils, suspensions, pastes, and semi-solids with nitrogen flushing for oxygen-sensitive formulations.

Can the line produce vegetarian supplement softgels?

Yes. HPMC and pullulan shell capability is standard across RG models, supporting halal and kosher clean-label formulations. Temperature and humidity are adjustable per material, so supplement brands can serve plant-based and vegetarian consumer segments without a separate production line.

What certifications support supplement factory compliance?

RG series machines are CE certified and built to cGMP, FDA 21 CFR Part 11, and ISO 9001 standards. Documentation includes material certificates, weld records, DQ/IQ/OQ/PQ protocols, and calibration certificates suitable for FDA, EMA, and Health Canada supplement filings.

How fast is die changeover for supplement variety?

Die roll changeover takes 15 to 30 minutes with a tool-free quick-release mechanism. A single RG machine produces oval, oblong, round, cylindrical, and custom shapes from 5 to 24 mm, letting supplement factories run multiple client formulations efficiently.

Product Gallery

Softgel Encapsulation Solutions for Dietary Supplement Factories - full machine view with control panel and production stations
Softgel Encapsulation Solutions for Dietary Supplement Factories - internal mechanism and key component detail
Softgel Encapsulation Solutions for Dietary Supplement Factories - finished products and application showcase

Technical Specifications

ParameterValueUnit
Capacity Range5,000-228,000caps/hr
Filling Accuracy+/-1-2%%
Optional Accuracy+/-1%%
Shell MaterialsGelatin, HPMC, pullulan
Contact Material316L stainless steel
Capsule Size5-24mm
Sealing PressureHydraulic 0.3-0.8MPa
Drying Conditions25 deg C, 30% RH, 4-8h
Die Changeover15-30min
ControlHMI with recipe management
CertificationsCE, cGMP, ISO 9001

Model Comparison: RG-100 vs RG-300 vs RG-500

FeatureRG-100RG-300RG-500
Capacity (caps/hr)5,000-10,00020,000-30,00040,000-60,000
Power (kW)4.54.5N/A listed
Min. Batch Size5002,0002,000-5,000
Filling Accuracy+/-2%+/-2% (+/-1% opt)+/-2% (+/-1% opt)
WeightN/A850 kg1,200 kg
Footprint1.2 x 0.8 m1.8 x 1.2 x 1.5 m2.5 x 1.5 m
OperationBatch/R&DMedium-scale24/7 continuous
Vegetarian ShellsHPMC/pullulan stdHPMC/pullulan stdHPMC/pullulan std
Nitrogen FlushingStandardStandardStandard
ApplicationR&D/clinicalCMO/supplementsIndustrial/pharma

Installation, Setup & Maintenance Guide

Planning the installation of a dietary supplement softgel line requires careful coordination between facility teams and equipment suppliers. Begin by confirming the cleanroom or GMP manufacturing space can maintain 22-26 deg C and 30-45% relative humidity, as temperature excursions affect shell material viscosity and capsule sealing quality. Secure three-phase electrical power and compressed air or nitrogen supply per the specifications of the chosen RG model. For supplement factories, the gelatin preparation area must be segregated from the filling zone to prevent cross-contamination. YohoAI includes 5-7 days of on-site installation and commissioning for the RG-100 through RG-500, with extended support for the RG-8800 turnkey line.

Daily supplement production on RG series equipment follows a structured operational sequence for quality assurance. Start each shift by verifying shell material temperature and viscosity against the approved recipe parameters stored in the HMI. Run a short pilot batch of 100-200 capsules to confirm filling accuracy and capsule seal integrity before committing to full production speed. Monitor nitrogen flushing pressure and hydraulic sealing at 0.3-0.8 MPa to ensure oxygen barrier performance, particularly critical for omega-3 and probiotic formulations. Check the drying tunnel conditions at 25 deg C and 30% RH every 2 hours and log capsule moisture content at the end of each drying cycle. Reject off-spec capsules using the automatic rejection system and record reject rates per batch for trend analysis.

Preventive maintenance for dietary supplement softgel lines must balance production throughput with equipment reliability. Weekly: perform CIP cleaning of the gelatin manifold and gear pump using food-grade cleaning agents, inspect die rolls for surface scoring that can cause shell damage or leaking capsules, and verify the hydraulic sealing system operates within the 0.3-0.8 MPa range. Monthly: replace all seals and O-rings in the filling circuit to prevent contamination of high-value supplement fills, calibrate the servo pump flow meter against the factory certificate, and check the nitrogen flushing system for leaks or pressure fluctuations. Quarterly maintenance covers full die roll dimensional inspection, HMI recipe database backup, and review of the maintenance log to identify recurring issues before they cause unplanned downtime.

Maintenance Checklist

  • Verify cleanroom conditions (22-26 deg C, 30-45% RH) and nitrogen supply before start-up
  • Confirm shell material temperature and viscosity against the approved recipe before each batch
  • Run a 100-200 capsule pilot batch and verify fill accuracy and seal integrity before full-speed production
  • Monitor drying tunnel conditions (25 deg C, 30% RH) and capsule moisture content every 2 hours
  • Perform CIP cleaning of gelatin manifold and gear pump weekly with food-grade agents
  • Replace seals and O-rings in the filling circuit monthly to prevent contamination
  • Calibrate servo pump flow meter and back up HMI recipe database quarterly

Related Models & Solutions

RG-100: 5,000-10,000 caps/hr

Laboratory softgel machine for formulation development and pilot batches

RG-300: 20,000-30,000 caps/hr

Most popular production model for medium-scale supplement manufacturers

RG-500: 40,000-60,000 caps/hr

Industrial softgel system for large-scale 24/7 supplement production